BD-PT5300

Inhibin β-E Rabbit Polyclonal Antibody

INHBE; Inhibin beta E chain; Activin beta-E chain

常规抗体

INHBE

Inhibin beta E chain

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

83729

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83729

P58166

http://www.uniprot.org/uniprotkb/P58166/entry

16326

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16326

O08717

http://www.uniprot.org/uniprot/O08717

83711

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83711

O88959

http://www.uniprot.org/uniprot/O88959

The antiserum was produced against synthesized peptide derived from the C-terminal region of human INHBE. AA range:301-350

Inhibin β-E Polyclonal Antibody detects endogenous levels of Inhibin β-E protein.

WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

38kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. Inhibins have been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. This gene may be upregulated under conditions of endoplasmic reticulum stress, and this protein may inhibit cellular proliferation and growth in pancreas and liver. [provided by RefSeq, Sep 2016],

Liver,Muscle,

Secreted .

Cytokine-cytokine receptor interaction;TGF-beta;

function:Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.,similarity:Belongs to the TGF-beta family.,subunit:Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.