产品名称
IL-29 Rabbit Polyclonal Antibody
别名
IL29; IFNL1; ZCYTO21; Interleukin-29; IL-29; Cytokine Zcyto21; Interferon lambda-1; IFN-lambda-1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=282618
Human Swissprot No.
Q8IU54
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IU54/entry
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human IL29. AA range:121-170
特异性
IL-29 Polyclonal Antibody detects endogenous levels of IL-29 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],
信号通路
Cytokine-cytokine receptor interaction;Jak_STAT;
功能
function:Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,online information:Interleukin-29 entry,similarity:Belongs to the IL-28/IL-29 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
