产品名称
VGF Rabbit Polyclonal Antibody
别名
VGF; Neurosecretory protein VGF
蛋白名称
Neurosecretory protein VGF
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7425
Human Swissprot No.
O15240
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15240/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29461
Rat Swissprot Link
http://www.uniprot.org/uniprot/P20156
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human VGF. AA range:451-500
特异性
VGF Polyclonal Antibody detects endogenous levels of VGF protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. [provided by RefSeq, Jul 2008],
组织表达
Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.
细胞定位
[Neurosecretory protein VGF]: Secreted . Cytoplasmic vesicle, secretory vesicle . Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
功能
function:May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.,subcellular location:Stored in secretory vesicles and then secreted.,tissue specificity:Expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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