产品名称
PSP Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5623
Human Swissprot No.
O60542
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O60542/entry
Mouse Swissprot No.
O70300
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70300
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25525
Rat Swissprot Link
http://www.uniprot.org/uniprot/O70301
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human PSPN. AA range:101-150
特异性
PSP Polyclonal Antibody detects endogenous levels of PSP protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
persephin(PSPN) Homo sapiens This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016],
功能
function:Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.,similarity:Belongs to the TGF-beta family. GDNF subfamily.,subunit:Homodimer; disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
