产品名称
Osteoglycin Rabbit Polyclonal Antibody
别名
OGN; OIF; SLRR3A; Mimecan; Osteoglycin; Osteoinductive factor; OIF
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4969
Human Swissprot No.
P20774
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P20774/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18295
Mouse Swissprot No.
Q62000
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62000
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human OGN. AA range:231-280
特异性
Osteoglycin Polyclonal Antibody detects endogenous levels of Osteoglycin protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
细胞定位
Secreted, extracellular space, extracellular matrix .
功能
function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class III subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Bone.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
