产品名称
CD241 Rabbit Polyclonal Antibody
别名
RHAG; RH50; Ammonium transporter Rh type A; Erythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh50A; Rhesus blood group family type A glycoprotein;Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group-associated ammonia channel; Rhesus blood group-associated glycoprotein; CD241
蛋白名称
Ammonium transporter Rh type A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6005
Human Swissprot No.
Q02094
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02094/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19743
Mouse Swissprot No.
Q9QUT0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QUT0
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=65207
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q7TNK7
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human RHAG. AA range:1-50
特异性
CD241 Polyclonal Antibody detects endogenous levels of CD241 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009],
细胞定位
Membrane ; Multi-pass membrane protein.
功能
disease:Defects in RHAG are the cause of regulator type Rh-null hemolytic anemia (RHN) [MIM:268150]; also called Rh-deficiency syndrome. RHN is a form of chronic hemolytic anemia in which the red blood cells have a stomatocytosis and spherocytosis morphology, an increased osmotic fragility, an altered ion transport system, and abnormal membrane phospholipid organization.,function:Associated with rhesus blood group antigen expression. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.,similarity:Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.,subunit:Heterotetramer.,tissue specificity:Erythrocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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