产品名称
GRIK4 Rabbit Polyclonal Antibody
别名
Glutamate receptor, ionotropic kainate 4 (Excitatory amino acid receptor 1) (EAA1) (Glutamate receptor KA-1) (KA1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.239% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2900
Human Swissprot No.
Q16099
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16099/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/110637
Mouse Swissprot No.
Q8BMF5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMF5
Rat Gene Link
https://www.uniprot.org/uniprot/24406
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q01812
免疫原
Synthesized peptide derived from human GRIK4 AA range: 466-516
特异性
This antibody detects endogenous levels of GRIK4 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
功能
function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Forms a heteromeric channel with GRIK1 or GRIK3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
