产品名称
CD300g Rabbit Polyclonal Antibody
别名
CD300LG; CLM9; TREM4; CMRF35-like molecule 9; CLM-9; CD300 antigen-like family member G; Triggering receptor expressed on myeloid cells 4; TREM-4; CD300g
蛋白名称
CMRF35-like molecule 9
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=146894
Human Swissprot No.
Q6UXG3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6UXG3/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=52685
Mouse Swissprot No.
Q1ERP8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q1ERP8
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD300LG. AA range:41-90
特异性
CD300g Polyclonal Antibody detects endogenous levels of CD300g protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the CD300 (see MIM 606786)-like (CD300L) family, such as CD300LG, are widely expressed on hematopoietic cells. All CD300L proteins are type I cell surface glycoproteins that contain a single immunoglobulin (Ig) V-like domain (Takatsu et al., 2006 [PubMed 16876123]).[supplied by OMIM, Mar 2008],
组织表达
Highly expressed in heart, skeletal muscle and placenta.
细胞定位
Apical cell membrane ; Single-pass type I membrane protein . Basolateral cell membrane ; Single-pass type I membrane protein . Endosome, multivesicular body membrane ; Single-pass type I membrane protein . Transcytoses across the cytoplasm. .
功能
domain:Ig-like V-type domain mediates binding to lymphocyte.,function:Receptor which may mediate L-selectin-dependent lymphocyte rollings. Binds SELL in a calcium dependent manner. Binds lymphocyte.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Highly expressed in heart, skeletal muscle and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
