产品名称
CD229 Rabbit Polyclonal Antibody
别名
LY9; CDABP0070; T-lymphocyte surface antigen Ly-9; Cell surface molecule Ly-9; Lymphocyte antigen 9; CD229
蛋白名称
T-lymphocyte surface antigen Ly-9
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4063
Human Swissprot No.
Q9HBG7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9HBG7/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17085
Mouse Swissprot No.
Q01965
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q01965
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LY9. AA range:261-310
特异性
CD229 Polyclonal Antibody detects endogenous levels of CD229 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008],
组织表达
Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
细胞定位
Membrane; Single-pass type I membrane protein. Cell membrane .
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
