产品名称
CD107a Rabbit Polyclonal Antibody
别名
LAMP1; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a
蛋白名称
Lysosome-associated membrane glycoprotein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3916
Human Swissprot No.
P11279
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P11279/entry
Mouse Swissprot No.
P11438
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P11438
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25328
Rat Swissprot Link
http://www.uniprot.org/uniprot/P14562
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260
特异性
CD107a Polyclonal Antibody detects endogenous levels of CD107a protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],
组织表达
Brain,Liver,Pancreas,Placenta,Plasma,Testis,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .
功能
function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
