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CD58 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5251
产品名称
CD58 Rabbit Polyclonal Antibody
别名
CD58; LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58
类别
常规抗体
基因名称
CD58
蛋白名称
Lymphocyte function-associated antigen 3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
965
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=965
Human Swissprot No.
P19256
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P19256/entry
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80
特异性
CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
预测分子量
27kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],
组织表达
Brain,Erythrocyte,
细胞定位
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.
信号通路
Cell adhesion molecules (CAMs);
功能
function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from K562 cells, using CD58 Antibody.

Western Blot analysis of K562 cells using CD58 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:100

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