产品名称
CD2 Rabbit Polyclonal Antibody
别名
CD2; SRBC; T-cell surface antigen CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2
蛋白名称
T-cell surface antigen CD2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=914
Human Swissprot No.
P06729
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P06729/entry
Mouse Swissprot No.
P08920
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P08920
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CD2. AA range:31-80
特异性
CD2 Polyclonal Antibody detects endogenous levels of CD2 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],
组织表达
Expressed in natural killer cells (at protein level).
细胞定位
Cell membrane ; Single-pass type I membrane protein .
信号通路
Cell adhesion molecules (CAMs);Hematopoietic cell lineage;
功能
function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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