产品名称
Lipocalin-1 Rabbit Polyclonal Antibody
别名
LCN1; VEGP; Lipocalin-1; Tear lipocalin; Tlc; Tear prealbumin; TP; Von Ebner gland protein; VEG protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3933
Human Swissprot No.
P31025
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P31025/entry
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LCN1. AA range:11-60
特异性
Lipocalin-1 Polyclonal Antibody detects endogenous levels of Lipocalin-1 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011],
组织表达
Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.
功能
caution:Could be the product of a pseudogene.,function:Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.,function:May bind a variety of ligands including lipids.,similarity:Belongs to the calycin superfamily. Lipocalin family.,subunit:Homodimer (By similarity). Binds to LMBR1L which may mediate its endocytosis.,tissue specificity:Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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