产品名称
Kallistatin Rabbit Polyclonal Antibody
别名
SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5267
Human Swissprot No.
P29622
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P29622/entry
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210
特异性
Kallistatin Polyclonal Antibody detects endogenous levels of Kallistatin protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
组织表达
Expressed by the liver and secreted in plasma.
功能
function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
