Cn|En

现货抗体产品库

FOXP1 Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PT5213
产品名称
FOXP1 Rabbit Polyclonal Antibody
别名
FOXP1; HSPC215; Forkhead box protein P1
类别
常规抗体
基因名称
FOXP1
蛋白名称
Forkhead box protein P1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
27086
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27086
Human Swissprot No.
Q9H334
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H334/entry
Mouse Gene ID
108655
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108655
Mouse Swissprot No.
P58462
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P58462
Rat Gene ID
297480
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=297480
Rat Swissprot No.
Q498D1
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q498D1
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP1. AA range:628-677
特异性
FOXP1 Polyclonal Antibody detects endogenous levels of FOXP1 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
预测分子量
75kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
组织表达
Isoform 8 is specifically expressed in embryonic stem cells.
细胞定位
Nucleus . Not found in the nucleolus. .
功能
alternative products:Additional isoforms seem to exist,disease:A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5.,domain:The leucine-zipper is required for dimerization and transcriptional repression.,function:Transcriptional repressor that plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Forms homodimers and heterodimers with FOXP2 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of K562 cells using FOXP1 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

Western Blot analysis of customer‘s using FOXP1 Antibody Polyclonal Antibody.

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded Human lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK