产品名称
P2X3 Rabbit Polyclonal Antibody
别名
P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5024
Human Swissprot No.
P56373
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P56373/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228139
Mouse Swissprot No.
Q3UR32
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UR32
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81739
Rat Swissprot Link
http://www.uniprot.org/uniprot/P49654
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130
特异性
P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:Receptor for ATP that acts as a ligand gated ion channel.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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