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P2X3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5211
产品名称
P2X3 Rabbit Polyclonal Antibody
别名
P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
类别
常规抗体
基因名称
P2RX3
蛋白名称
P2X purinoceptor 3
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5024
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5024
Human Swissprot No.
P56373
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P56373/entry
Mouse Gene ID
228139
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228139
Mouse Swissprot No.
Q3UR32
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UR32
Rat Gene ID
81739
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81739
Rat Swissprot No.
P49654
Rat Swissprot Link
http://www.uniprot.org/uniprot/P49654
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130
特异性
P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
预测分子量
44kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],
组织表达
Heart,
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:Receptor for ATP that acts as a ligand gated ion channel.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from K562 cells, using P2RX3 Antibody.

Western Blot analysis of K562 cells using P2X3 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-heart, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-heart, antibody was diluted at 1:100

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