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CRP Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT5196
产品名称
CRP Rabbit Polyclonal Antibody
别名
CRP; PTX1; C-reactive protein
类别
常规抗体
基因名称
CRP
蛋白名称
C-reactive protein
推荐应用
WB
反应种属
Human,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
1401
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1401
Human Swissprot No.
P02741
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P02741/entry
Mouse Swissprot No.
P14847
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P14847
Rat Gene ID
25419
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25419
Rat Swissprot No.
P48199
Rat Swissprot Link
http://www.uniprot.org/uniprot/P48199
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human CRP. AA range:101-150
特异性
CRP Polyclonal Antibody detects endogenous levels of CRP protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
预测分子量
25kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
C-reactive protein(CRP) Homo sapiens The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009],
组织表达
Found in plasma.
细胞定位
Secreted.
功能
cofactor:Binds 2 calcium ions per subunit.,function:Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.,induction:The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.,mass spectrometry: Ref.14,miscellaneous:This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.,online information:C-reactive protein entry,online information:No more Christmas pudding? - Issue 30 of January 2003,similarity:Belongs to the pentaxin family.,similarity:Contains 1 pentaxin domain.,subunit:Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.,tissue specificity:Found in plasma.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from mouse liver cells, using CRP Antibody.

Western Blot analysis of mouse liver cells using CRP Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-liver, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-liver, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded Human Liver. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human Liver. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human Liver. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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