BD-PT5196-CRP Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

CRP Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT5196

产品名称

CRP Rabbit Polyclonal Antibody

别名

CRP; PTX1; C-reactive protein

类别

常规抗体

基因名称

CRP

蛋白名称

C-reactive protein

推荐应用

反应种属

Human,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

1401

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1401

Human Swissprot No.

P02741

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P02741/entry

Mouse Swissprot No.

P14847

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P14847

Rat Gene ID

25419

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25419

Rat Swissprot No.

P48199

Rat Swissprot Link

http://www.uniprot.org/uniprot/P48199

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human CRP. AA range:101-150

特异性

CRP Polyclonal Antibody detects endogenous levels of CRP protein.

稀释度

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200

预测分子量

25kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

C-reactive protein(CRP) Homo sapiens The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009],

组织表达

Found in plasma.

细胞定位

Secreted.

功能

cofactor:Binds 2 calcium ions per subunit.,function:Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.,induction:The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.,mass spectrometry: Ref.14,miscellaneous:This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.,online information:C-reactive protein entry,online information:No more Christmas pudding? - Issue 30 of January 2003,similarity:Belongs to the pentaxin family.,similarity:Contains 1 pentaxin domain.,subunit:Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.,tissue specificity:Found in plasma.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from mouse liver cells, using CRP Antibody.

Western Blot analysis of mouse liver cells using CRP Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-liver, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded Human Liver. 1, Antibody was diluted at 1:200（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.