BD-PT5195-HoxD3 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

HoxD3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT5195

产品名称

HoxD3 Rabbit Polyclonal Antibody

别名

HOXD3; HOX1D; HOX4A; Homeobox protein Hox-D3; Homeobox protein Hox-4A

类别

常规抗体

基因名称

HOXD3

蛋白名称

Homeobox protein Hox-D3

推荐应用

反应种属

Human,Mouse,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

3232

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3232

Human Swissprot No.

P31249

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P31249/entry

Mouse Gene ID

15434

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15434

Mouse Swissprot No.

P09027

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P09027

Rat Swissprot No.

P18867

Rat Swissprot Link

http://www.uniprot.org/uniprot/P18867

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human HOXD3. AA range:211-260

特异性

HoxD3 Polyclonal Antibody detects endogenous levels of HoxD3 protein.

稀释度

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200

预测分子量

45kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes. [provided by RefSeq, Jul 2008],

组织表达

Brain,Lung,

细胞定位

Nucleus.

功能

caution:It is uncertain whether Met-1 or Met-17 is the initiator.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from HepG2 cells, using HOXD3 Antibody.

Western Blot analysis of HepG2 cells using HoxD3 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100