产品名称
LCTL Rabbit Polyclonal Antibody
别名
Lactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)
基因名称
LCTL KLPH UNQ3022/PRO9820
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.143% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/197021
Human Swissprot No.
Q6UWM7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6UWM7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/235435
Mouse Swissprot No.
Q8K1F9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K1F9
免疫原
Synthesized peptide derived from human LCTL AA range: 450-500
特异性
This antibody detects endogenous levels of LCTL at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
功能
caution:Probably inactive as a glycosidase since it lacks the essential active site Glu at position 201.,similarity:Belongs to the glycosyl hydrolase 1 family.,similarity:Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
