产品名称
Aldolase C Rabbit Polyclonal Antibody
别名
ALDOC; ALDC; Fructose-bisphosphate aldolase C; Brain-type aldolase
蛋白名称
Fructose-bisphosphate aldolase C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=230
Human Swissprot No.
P09972
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P09972/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11676
Mouse Swissprot No.
P05063
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P05063
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24191
Rat Swissprot Link
http://www.uniprot.org/uniprot/P09117
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDOC. AA range:21-70
特异性
Aldolase C Polyclonal Antibody detects endogenous levels of Aldolase C protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008],
组织表达
Brain,Colon,Epithelium,Eye,Uterus,
细胞定位
mitochondrion,cytosol,cytoskeleton,extracellular exosome,
信号通路
Glycolysis / Gluconeogenesis;Pentose phosphate pathway;Fructose and mannose metabolism;
功能
catalytic activity:D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.,miscellaneous:In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.,similarity:Belongs to the class I fructose-bisphosphate aldolase family.,subunit:Homotetramer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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