产品名称
FGF-18 Rabbit Polyclonal Antibody
别名
FGF18; Fibroblast growth factor 18; FGF-18; zFGF5
蛋白名称
Fibroblast growth factor 18
反应种属
Human,Mouse,Rat,Sheep
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8817
Human Swissprot No.
O76093
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O76093/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14172
Mouse Swissprot No.
O89101
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O89101
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29369
Rat Swissprot Link
http://www.uniprot.org/uniprot/O88182
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human FGF18. AA range:158-207
特异性
FGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008],
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;Regulates Actin and Cytoskeleton;Pathways in cancer;Melanoma;
功能
function:Stimulates hepatic and intestinal proliferation.,similarity:Belongs to the heparin-binding growth factors family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
