BD-PT5177-MK Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

MK Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT5177

产品名称

MK Rabbit Polyclonal Antibody

别名

MDK; MK1; NEGF2; Midkine; MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein

类别

常规抗体

基因名称

MDK

蛋白名称

Midkine

推荐应用

反应种属

Human,Rat

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

4192

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4192

Human Swissprot No.

P21741

Human Swissprot Link

http://www.uniprot.org/uniprotkb/P21741/entry

Mouse Swissprot No.

P12025

Mouse Swissprot Link

http://www.uniprot.org/uniprot/P12025

Rat Gene ID

81517

Rat Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81517

Rat Swissprot No.

Q9R1S9

Rat Swissprot Link

http://www.uniprot.org/uniprot/Q9R1S9

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human MDK. AA range:94-143

特异性

MK Polyclonal Antibody detects endogenous levels of MK protein.

稀释度

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200

预测分子量

18kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012],

组织表达

Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.

细胞定位

Secreted.

功能

function:Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.,induction:By heparin and retinoic acid.,similarity:Belongs to the pleiotrophin family.,subunit:Homodimer.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from SW480 cells, using MDK Antibody.

Western Blot analysis of SW480, MCF7, PC-3, Raji, K562, mouse eye, mouse kidney cells using MK Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded Human Prostate. 1, Antibody was diluted at 1:100（4°,overnight）. 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200（room temperature, 30min）.