产品名称
IFN-α1 Rabbit Polyclonal Antibody
别名
IFNA1; IFNA13; Interferon alpha-1/13; IFN-alpha-1/13; Interferon alpha-D; LeIF D
蛋白名称
Interferon alpha-1/13
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3439
Human Swissprot No.
P01562
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P01562/entry
Mouse Swissprot No.
P01572
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P01572
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IFNA1/13. AA range:140-189
特异性
IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
组织表达
Cerebellum,Leukocyte,
信号通路
Cytokine-cytokine receptor interaction;Regulation of autophagy;Antigen processing and presentation;Toll_Like;RIG-I-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Natural killer cell mediated cytotoxicity;Autoimmune thyroid disease;
功能
function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
