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PGTA Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN3188
产品名称
PGTA Rabbit Polyclonal Antibody
别名
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
类别
常规抗体
基因名称
RABGGTA
蛋白名称
PGTA
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% New type preservative N.
Human Gene ID
5875
Human Gene Link
https://www.uniprot.org/uniprot/5875
Human Swissprot No.
Q92696
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92696/entry
Mouse Gene ID
56187
Mouse Gene Link
https://www.uniprot.org/uniprot/56187
Mouse Swissprot No.
Q9JHK4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHK4
Rat Gene ID
58983
Rat Gene Link
https://www.uniprot.org/uniprot/58983
Rat Swissprot No.
Q08602
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q08602
免疫原
Synthesized peptide derived from human PGTA AA range: 312-362
特异性
This antibody detects endogenous levels of PGTA at Human/Mouse/Rat
稀释度
WB 1:500-2000
预测分子量
60kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
组织表达
Fetal brain,Lung,Thymus,Tongue,
细胞定位
plasma membrane,Rab-protein geranylgeranyltransferase complex,
功能
catalytic activity:Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.,cofactor:Binds 1 zinc ion per dimer.,enzyme regulation:The enzymatic reaction requires the aid of a Rab escort protein (also called component A).,function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.,similarity:Belongs to the protein prenyltransferase subunit alpha family.,similarity:Contains 6 PFTA repeats.,subunit:Heterodimer of an alpha and a beta subunit, collectively called component B.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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