产品名称
PGTA Rabbit Polyclonal Antibody
别名
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5875
Human Swissprot No.
Q92696
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92696/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/56187
Mouse Swissprot No.
Q9JHK4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JHK4
Rat Gene Link
https://www.uniprot.org/uniprot/58983
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q08602
免疫原
Synthesized peptide derived from human PGTA AA range: 312-362
特异性
This antibody detects endogenous levels of PGTA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Fetal brain,Lung,Thymus,Tongue,
细胞定位
plasma membrane,Rab-protein geranylgeranyltransferase complex,
功能
catalytic activity:Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.,cofactor:Binds 1 zinc ion per dimer.,enzyme regulation:The enzymatic reaction requires the aid of a Rab escort protein (also called component A).,function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.,similarity:Belongs to the protein prenyltransferase subunit alpha family.,similarity:Contains 6 PFTA repeats.,subunit:Heterodimer of an alpha and a beta subunit, collectively called component B.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
