产品名称
IFN-α1 Rabbit Polyclonal Antibody
别名
IFNA1; IFNA13; Interferon alpha-1/13; IFN-alpha-1/13; Interferon alpha-D; LeIF D
蛋白名称
Interferon alpha-1/13
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3439
Human Swissprot No.
P01562
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P01562/entry
Mouse Swissprot No.
P01572
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P01572
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IFNA1/13. AA range:140-189
特异性
IFN-α1 Polyclonal Antibody detects endogenous levels of IFN-α1 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
组织表达
Cerebellum,Leukocyte,
信号通路
Cytokine-cytokine receptor interaction;Regulation of autophagy;Antigen processing and presentation;Toll_Like;RIG-I-like receptor;Cytosolic DNA-sensing pathway;Jak_STAT;Natural killer cell mediated cytotoxicity;Autoimmune thyroid disease;
功能
function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
