BD-PT5150-Eotaxin-3 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Eotaxin-3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT5150

产品名称

Eotaxin-3 Rabbit Polyclonal Antibody

别名

CCL26; SCYA26; C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1

类别

常规抗体

基因名称

CCL26

蛋白名称

C-C motif chemokine 26

推荐应用

反应种属

Human,Rat,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

10344

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10344

Human Swissprot No.

Q9Y258

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q9Y258/entry

免疫原

The antiserum was produced against synthesized peptide derived from the Internal region of human CCL26. AA range:31-80

特异性

Eotaxin-3 Polyclonal Antibody detects endogenous levels of Eotaxin-3 protein.

稀释度

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200

预测分子量

12kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008],

组织表达

Ubiquitously expressed at low levels in various tissues including heart and ovary.

细胞定位

Secreted .

信号通路

Cytokine-cytokine receptor interaction;Chemokine;

功能

function:Chemotactic for eosinophils and basophils. Binds to CCR3.,online information:CCL26 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,subunit:Monomer.,tissue specificity:Ubiquitously expressed at low levels in various tissues including heart and ovary.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from PC-3 cells, using CCL26 Antibody.

Western Blot analysis of PC-3, A549, OVCAR3, mouse colon cells using Eotaxin-3 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100