BD-PT5147

ET-1 Rabbit Polyclonal Antibody

EDN1; Endothelin-1; Preproendothelin-1; PPET1

常规抗体

EDN1

Endothelin-1

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1906

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1906

P05305

http://www.uniprot.org/uniprotkb/P05305/entry

P22387

http://www.uniprot.org/uniprot/P22387

The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180

ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.

IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

25kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Secreted.

Melanogenesis;

function:Endothelins are endothelium-derived vasoconstrictor peptides.,online information:Endothelin entry,similarity:Belongs to the endothelin/sarafotoxin family.,tissue specificity:Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.