产品名称
ET-1 Rabbit Polyclonal Antibody
别名
EDN1; Endothelin-1; Preproendothelin-1; PPET1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1906
Human Swissprot No.
P05305
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P05305/entry
Mouse Swissprot No.
P22387
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P22387
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
特异性
ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
稀释度
IHC-p: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
组织表达
Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
功能
function:Endothelins are endothelium-derived vasoconstrictor peptides.,online information:Endothelin entry,similarity:Belongs to the endothelin/sarafotoxin family.,tissue specificity:Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.