产品名称
TAPT1 Rabbit Polyclonal Antibody
别名
Transmembrane anterior posterior transformation protein 1 homolog (Cytomegalovirus partial fusion receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.149% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/202018
Human Swissprot No.
Q6NXT6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6NXT6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/231225
Mouse Swissprot No.
Q4VBD2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q4VBD2
免疫原
Synthesized peptide derived from human TAPT1 AA range: 295-345
特异性
This antibody detects endogenous levels of TAPT1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Membrane ; Multi-pass membrane protein .
功能
function:May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169.,similarity:Belongs to the TAPT1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
