产品名称
Sg III Rabbit Polyclonal Antibody
别名
SCG3; Secretogranin-3; Secretogranin III; SgIII
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29106
Human Swissprot No.
Q8WXD2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WXD2/entry
Mouse Swissprot No.
P47867
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P47867
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116635
Rat Swissprot Link
http://www.uniprot.org/uniprot/P47868
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3. AA range:21-70
特异性
Sg III Polyclonal Antibody detects endogenous levels of Sg III protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
secretogranin III(SCG3) Homo sapiens The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
组织表达
Expressed in brain, heart, kidney, liver and skeletal muscle.
细胞定位
Cytoplasmic vesicle, secretory vesicle . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein . Secreted . Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. .
功能
subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in brain, heart, kidney, liver and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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