产品名称
HSPBAP1 Rabbit Polyclonal Antibody
别名
HSPBAP1; PASS1; HSPB1-associated protein 1; 27 kDa heat shock protein-associated protein 1; Protein associated with small stress protein 1
蛋白名称
HSPB1-associated protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79663
Human Swissprot No.
Q96EW2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96EW2/entry
Mouse Swissprot No.
Q8BK58
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BK58
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370
特异性
HSPBAP1 Polyclonal Antibody detects endogenous levels of HSPBAP1 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011],
功能
disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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