BD-PT5136

Claudin-17 Rabbit Polyclonal Antibody

CLDN17; Claudin-17

常规抗体

CLDN17

Claudin-17

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

26285

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26285

P56750

http://www.uniprot.org/uniprotkb/P56750/entry

239931

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=239931

Q8BXA6

http://www.uniprot.org/uniprot/Q8BXA6

Synthesized peptide derived from Claudin-17 . at AA range: 150-230

Claudin-17 Polyclonal Antibody detects endogenous levels of Claudin-17 protein.

WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

24kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010],

In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level).

Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .

Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;

function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.