产品名称
Hepassocin Rabbit Polyclonal Antibody
别名
FGL1; HFREP1; Fibrinogen-like protein 1; HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
蛋白名称
Fibrinogen-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2267
Human Swissprot No.
Q08830
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q08830/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=234199
Mouse Swissprot No.
Q71KU9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q71KU9
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5M8C6
免疫原
Synthesized peptide derived from the Internal region of human Hepassocin.
特异性
Hepassocin Polyclonal Antibody detects endogenous levels of Hepassocin protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
fibrinogen like 1(FGL1) Homo sapiens Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008],
组织表达
Under normal conditions, liver-specific.
细胞定位
Secreted . Secreted in the blood plasma. .
功能
function:Has hepatocyte mitogenic activity.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Homodimer.,tissue specificity:Liver specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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