产品名称
DPP7 Rabbit Polyclonal Antibody
别名
DPP7; DPP2; QPP; Dipeptidyl peptidase 2; Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; Quiescent cell proline dipeptidase
蛋白名称
Dipeptidyl peptidase 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29952
Human Swissprot No.
Q9UHL4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UHL4/entry
Mouse Swissprot No.
Q9ET22
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ET22
免疫原
Synthesized peptide derived from the C-terminal region of human DPP7.
特异性
DPP7 Polyclonal Antibody detects endogenous levels of DPP7 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008],
组织表达
Detected in seminal plasma (at protein level).
细胞定位
Lysosome . Cytoplasmic vesicle . Secreted .
功能
catalytic activity:Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.,function:Plays an important role in the degradation of some oligopeptides.,PTM:N-glycosylated.,similarity:Belongs to the peptidase S28 family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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