Cn|En

现货抗体产品库

Chymase Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PT5123
产品名称
Chymase Rabbit Polyclonal Antibody
别名
CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I
类别
常规抗体
基因名称
CMA1
蛋白名称
Chymase
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
1215
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1215
Human Swissprot No.
P23946
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P23946/entry
Mouse Swissprot No.
P21844
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P21844
免疫原
Synthesized peptide derived from the Internal region of human Chymase.
特异性
Chymase Polyclonal Antibody detects endogenous levels of Chymase protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
预测分子量
27kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
chymase 1(CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],
组织表达
Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions.
细胞定位
Secreted. Cytoplasmic granule. Mast cell granules.
信号通路
Renin-angiotensin system;
功能
catalytic activity:Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.,function:Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,subcellular location:Mast cell granules.,tissue specificity:Mast cells in lung, heart, skin and placenta.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western Blot analysis of mouse lung cells using Chymase Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK