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AF9 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PN3195
产品名称
AF9 Rabbit Polyclonal Antibody
别名
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
类别
常规抗体
基因名称
MLLT3 AF9 YEATS3
蛋白名称
AF9
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.153% New type preservative N.
Human Gene ID
4300
Human Gene Link
https://www.uniprot.org/uniprot/4300
Human Swissprot No.
P42568
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P42568/entry
Mouse Gene ID
70122
Mouse Gene Link
https://www.uniprot.org/uniprot/70122
Mouse Swissprot No.
A2AM29
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2AM29
免疫原
Synthesized peptide derived from human AF9 AA range: 328-378
特异性
This antibody detects endogenous levels of AF9 at Human/Mouse
稀释度
WB 1:500-2000
预测分子量
60kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
组织表达
Enriched in undifferentiated hematopoietic stem cells in fetal liver, cord blood and bone marrow.
细胞定位
Nucleus . Chromosome . Colocalizes with acylated histone H3 (PubMed:25417107, PubMed:27105114). Colocalizes with histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). .
功能
disease:A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein.,similarity:Contains 1 YEATS domain.,subunit:Interacts with BCOR. Interacts with CBX8.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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