产品名称
AF9 Rabbit Polyclonal Antibody
别名
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.153% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4300
Human Swissprot No.
P42568
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P42568/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/70122
Mouse Swissprot No.
A2AM29
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A2AM29
免疫原
Synthesized peptide derived from human AF9 AA range: 328-378
特异性
This antibody detects endogenous levels of AF9 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Enriched in undifferentiated hematopoietic stem cells in fetal liver, cord blood and bone marrow.
细胞定位
Nucleus . Chromosome . Colocalizes with acylated histone H3 (PubMed:25417107, PubMed:27105114). Colocalizes with histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). .
功能
disease:A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein.,similarity:Contains 1 YEATS domain.,subunit:Interacts with BCOR. Interacts with CBX8.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
