产品名称
SCP-2 Rabbit Polyclonal Antibody
别名
SYCP2; SCP2; Synaptonemal complex protein 2; SCP-2; Synaptonemal complex lateral element protein; hsSCP2
蛋白名称
Synaptonemal complex protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10388
Human Swissprot No.
Q9BX26
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BX26/entry
Mouse Swissprot No.
Q9CUU3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CUU3
免疫原
Synthesized peptide derived from the Internal region of human SCP-2.
特异性
SCP-2 Polyclonal Antibody detects endogenous levels of SCP-2 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . In axial/lateral elements of the tripartite segments of synaptonemal complexes. .
功能
function:Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.,similarity:Belongs to the SYCP2 family.,subcellular location:In axial/lateral elements of the tripartite segments of synaptonemal complexes.,subunit:Heterodimer with SYCP3. Interacts with SYCP3, SMC1A and SMC3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
