产品名称
Hepassocin Rabbit Polyclonal Antibody
别名
FGL1; HFREP1; Fibrinogen-like protein 1; HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
蛋白名称
Fibrinogen-like protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2267
Human Swissprot No.
Q08830
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q08830/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=234199
Mouse Swissprot No.
Q71KU9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q71KU9
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5M8C6
免疫原
Synthesized peptide derived from the Internal region of human Hepassocin.
特异性
Hepassocin Polyclonal Antibody detects endogenous levels of Hepassocin protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
fibrinogen like 1(FGL1) Homo sapiens Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008],
组织表达
Under normal conditions, liver-specific.
细胞定位
Secreted . Secreted in the blood plasma. .
功能
function:Has hepatocyte mitogenic activity.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Homodimer.,tissue specificity:Liver specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.