产品名称
HSP77/76 Rabbit Polyclonal Antibody
别名
HSPA7; HSP70B; Putative heat shock 70 kDa protein 7; Heat shock 70 kDa protein B; HSPA6; HSP70B'; Heat shock 70 kDa protein 6; Heat shock 70 kDa protein B'
蛋白名称
Heat shock 70 kDa protein 6/Putative heat shock 70 kDa protein 7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3310
Human Swissprot No.
P48741
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P48741/entry
免疫原
Synthesized peptide derived from the Internal region of human HSP77/76.
特异性
HSP77/76 Polyclonal Antibody detects endogenous levels of HSP77/76 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,
组织表达
Cerebellum,Lung,Ovary,Skin,
细胞定位
COP9 signalosome,extracellular exosome,blood microparticle,
功能
caution:Could be the product of a pseudogene.,function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,induction:Only at higher temperatures, and no basal expression.,similarity:Belongs to the heat shock protein 70 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
