产品名称
DNA Pol μ Rabbit Polyclonal Antibody
别名
POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase
蛋白名称
DNA-directed DNA/RNA polymerase mu
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27434
Human Swissprot No.
Q9NP87
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NP87/entry
Mouse Swissprot No.
Q9JIW4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JIW4
免疫原
Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
特异性
DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
组织表达
Expressed in a number of tissues. Abundant in thymus.
信号通路
Non-homologous end-joining;
功能
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
