产品名称
SCML2 Rabbit Polyclonal Antibody
别名
SCML2; Sex comb on midleg-like protein 2
蛋白名称
Sex comb on midleg-like protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10389
Human Swissprot No.
Q9UQR0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UQR0/entry
免疫原
Synthesized peptide derived from the Internal region of human SCML2.
特异性
SCML2 Polyclonal Antibody detects endogenous levels of SCML2 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010],
组织表达
Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.
功能
function:Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SCM family.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 MBT repeats.,tissue specificity:Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
