BD-PT5100

RASSF8 Rabbit Polyclonal Antibody

RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

常规抗体

RASSF8

Ras association domain-containing protein 8

WB

Human,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

11228

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11228

Q8NHQ8

http://www.uniprot.org/uniprotkb/Q8NHQ8/entry

Q8CJ96

http://www.uniprot.org/uniprot/Q8CJ96

Synthesized peptide derived from RASSF8 . at AA range: 60-140

RASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein.

WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

48kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.

disease:A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM:608180]. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.,similarity:Contains 1 Ras-associating domain.,tissue specificity:Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.