产品名称
S13A5 Rabbit Polyclonal Antibody
别名
Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.157% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/284111
Human Swissprot No.
Q86YT5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86YT5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/237831
Mouse Swissprot No.
Q67BT3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q67BT3
Rat Gene Link
https://www.uniprot.org/uniprot/266998
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CJ44
免疫原
Synthesized peptide derived from human S13A5 AA range: 313-363
特异性
This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],
组织表达
Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.,similarity:Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.,tissue specificity:Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
