产品名称
NTT4 Rabbit Polyclonal Antibody
别名
SLC6A17; NTT4; Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17
蛋白名称
Sodium-dependent neutral amino acid transporter SLC6A17
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=388662
Human Swissprot No.
Q9H1V8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H1V8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=229706
Mouse Swissprot No.
Q8BJI1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BJI1
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=613226
Rat Swissprot Link
http://www.uniprot.org/uniprot/P31662
免疫原
Synthesized peptide derived from NTT4 . at AA range: 240-320
特异性
NTT4 Polyclonal Antibody detects endogenous levels of NTT4 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008],
细胞定位
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse . Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals. .
功能
function:Not yet known, orphan transporter.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
