BD-PT5084

TudorSN Rabbit Polyclonal Antibody

SND1; TDRD11; Staphylococcal nuclease domain-containing protein 1; 100 kDa coactivator; EBNA2 coactivator p100; Tudor domain-containing protein 11; p100 co-activator

常规抗体

SND1

Staphylococcal nuclease domain-containing protein 1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

27044

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27044

Q7KZF4

http://www.uniprot.org/uniprotkb/Q7KZF4/entry

56463

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56463

Q78PY7

http://www.uniprot.org/uniprot/Q78PY7

64635

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64635

Q66X93

http://www.uniprot.org/uniprot/Q66X93

Synthesized peptide derived from the Internal region of human TudorSN.

TudorSN Polyclonal Antibody detects endogenous levels of TudorSN protein.

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:40000.. IF 1:50-200

101kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016],

Ubiquitously expressed.

Cytoplasm . Nucleus . Melanosome . In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .

function:Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).,PTM:Phosphorylated by PIM1 in vitro.,sequence caution:The frameshift leads to wrong initation.,similarity:Contains 1 Tudor domain.,similarity:Contains 4 TNase-like domains.,subcellular location:In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Binds to acidic transactivation domain of EBNA2. Interacts with EAV NSP1. Interacts with GTF2E1 and GTF2E2. Forms a ternary complex with STAT6 and POLR2A. Interacts with STAT5.,tissue specificity:Ubiquitously expressed.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.