BD-PT5080

UBE4A Rabbit Polyclonal Antibody

UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A

常规抗体

UBE4A

Ubiquitin conjugation factor E4 A

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

9354

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9354

Q14139

http://www.uniprot.org/uniprotkb/Q14139/entry

315608

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=315608

Q6P7A2

http://www.uniprot.org/uniprot/Q6P7A2

Synthesized peptide derived from the N-terminal region of human UBE4A.

UBE4A Polyclonal Antibody detects endogenous levels of UBE4A protein.

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:10000.. IF 1:50-200

122kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],

Bone marrow,Platelet,Skeletal muscle,

Cytoplasm .

Ubiquitin mediated proteolysis;

function:Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the ubiquitin conjugation factor E4 family.,similarity:Contains 1 U-box domain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.