产品名称
SV2C Rabbit Polyclonal Antibody
别名
SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C
蛋白名称
Synaptic vesicle glycoprotein 2C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22987
Human Swissprot No.
Q496J9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q496J9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75209
Mouse Swissprot No.
Q69ZS6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q69ZS6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29643
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9Z2I6
免疫原
Synthesized peptide derived from the Internal region of human SV2C. AA range 330-390
特异性
SV2C Polyclonal Antibody detects endogenous levels of SV2C protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,
细胞定位
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. .
信号通路
ECM-receptor interaction;
功能
function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
