产品名称
Rab 26 Rabbit Polyclonal Antibody
别名
RAB26; Ras-related protein Rab-26
蛋白名称
Ras-related protein Rab-26
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25837
Human Swissprot No.
Q9ULW5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9ULW5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=328778
Mouse Swissprot No.
Q504M8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q504M8
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171111
Rat Swissprot Link
http://www.uniprot.org/uniprot/P51156
免疫原
Synthesized peptide derived from Rab 26 . at AA range: 180-256
特异性
Rab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein.
稀释度
WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010],
组织表达
Predominantly expressed in brain.
细胞定位
Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. .
功能
function:Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Predominantly expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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