产品名称
PDP2 Rabbit Polyclonal Antibody
别名
PDP2; KIAA1348; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; PDP 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2
蛋白名称
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57546
Human Swissprot No.
Q9P2J9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9P2J9/entry
免疫原
Synthesized peptide derived from PDP2 . at AA range: 70-150
特异性
PDP2 Polyclonal Antibody detects endogenous levels of PDP2 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016],
细胞定位
Mitochondrion matrix .
功能
catalytic activity:[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,similarity:Belongs to the PP2C family.,subunit:Heterodimer of a catalytic subunit and a FAD protein of unknown function.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.