产品名称
HGFA Rabbit Polyclonal Antibody
别名
HGFAC; Hepatocyte growth factor activator; HGF activator; HGFA
蛋白名称
Hepatocyte growth factor activator
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3083
Human Swissprot No.
Q04756
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q04756/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54426
Mouse Swissprot No.
Q9R098
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R098
免疫原
Synthesized peptide derived from the C-terminal region of human HGFA.
特异性
HGFA Polyclonal Antibody detects endogenous levels of HGFA protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
功能
caution:It is uncertain whether Met-1 is the initiator.,function:Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 fibronectin type-I domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer of a short chain and a long chain linked by a disulfide bond.,tissue specificity:Liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
