产品名称
FAIM2 Rabbit Polyclonal Antibody
别名
FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23017
Human Swissprot No.
Q9BWQ8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BWQ8/entry
Mouse Swissprot No.
Q8K097
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K097
免疫原
Synthesized peptide derived from the N-terminal region of human FAIM2.
特异性
FAIM2 Polyclonal Antibody detects endogenous levels of FAIM2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
组织表达
Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus.
细胞定位
Cell membrane ; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane .
功能
function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.