产品名称
Rab 26 Rabbit Polyclonal Antibody
别名
RAB26; Ras-related protein Rab-26
蛋白名称
Ras-related protein Rab-26
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25837
Human Swissprot No.
Q9ULW5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9ULW5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=328778
Mouse Swissprot No.
Q504M8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q504M8
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171111
Rat Swissprot Link
http://www.uniprot.org/uniprot/P51156
免疫原
Synthesized peptide derived from Rab 26 . at AA range: 180-256
特异性
Rab 26 Polyclonal Antibody detects endogenous levels of Rab 26 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010],
组织表达
Predominantly expressed in brain.
细胞定位
Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Not localized at the plasma membrane (By similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location. .
功能
function:Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Predominantly expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.